What is IHBR Full Form in Medical?

The IHBR Full Form in Medical term is Intrahepatic Biliary Radicals. They refer to the smaller bile ducts found within the liver that transfer bile from liver cells (hepatocytes) to bigger bile ducts, which eventually drain into the duodenum for digestion. These bile ducts form a complicated network, starting with small ductules within the liver and proceeding to bigger intrahepatic bile ducts. They have an important function in the formation of bile, which is required for fat digestion and absorption.

Structure and functions:

The intrahepatic biliary system comprises of small bile ducts called biliary radicals that are surrounded by hepatocytes. These ducts are coated by epithelial cells, which aid in the movement of bile and guard against hazardous substances. Bile goes from the hepatocytes through the biliary radicals, combining with bile produced by other regions of the liver before draining into bigger channels that eventually form the common hepatic duct, which connects to the common bile duct.

IHBR Pathology:

Disorders of the intrahepatic biliary radicals can cause a range of disorders, the most prevalent of which is primary biliary cholangitis, a chronic autoimmune illness affecting the intrahepatic bile ducts. PBC causes gradual inflammation and death of the bile ducts, resulting in decreased bile flow, liver damage, and, eventually, cirrhosis. Another disorder that can impact the intrahepatic biliary system is intrahepatic cholangiocarcinoma, which is a kind of cancer that develops in the bile ducts of the liver.