What is the Full Form of CBNAAT in Medical?

The Full Form of CBNAAT in Medical is a Cartridge-based Nucleic Acid Amplification Test. A quick molecular test for diagnosis is the CBNAAT. The purpose of this screening procedure is to evaluate tuberculosis, or TB, as well as identify resistance towards rifampicin within TB patients. Since the year 1982, the diagnosis of tuberculosis has changed and continues to change. The symptoms of tuberculosis include weakness, co-morbidities, and poverty. Because traditional techniques had a certain number of cases to generate the desired outcome, diagnosing tuberculosis using these methods proved challenging. A test that could overcome the drawbacks of the other traditional method had to be created.

Features of CBNAAT:

• By using the Polymerase Chain Re (PCR) method, the CB-NAAT technique finds DNA sequences unique to the tuberculosis-Mycobacterium causing rifampicin resistance.
• Mycobacterium tuberculosis bacilli are concentrated from samples of sputum, their genomic material is separated by sonication, and the DNA that makes up the genome is then amplified using PCR. Utilizing fluorescent probes known as molecular beacons, the procedure finds clinically significant abnormalities in the RNA-polymerase beta genes in M. tuberculosis genomes that cause resistance to rifampicin immediately.